Small business rule changes · compliance updates · daily

The Small Business
Rule Change Brief

Vol. 1 · No. 1086

Wednesday, August 26, 2026

1086 issues in archive

Rule lifecycle · DOCKET:Docket No. DEA-1644

Schedules of Controlled Substances: Temporary Placement of Mitragynine Pseudoindoxyl, MGM-15, and MGM-16 in Schedule I

Justice Department, Drug Enforcement Administration — observed across 2 documents over 51 days. Use the source documents below before deciding whether this affects your business.

In plain English

The Drug Enforcement Administration proposes to ban three chemical substances—mitragynine pseudoindoxyl, MGM-15, and MGM-16—making them illegal to make, sell, or own. If your business sells or manufactures products containing these substances, monitor this rule and prepare to stop selling them if the proposal is approved.

First seen

Jul 6, 2026

Last seen

Aug 26, 2026

Latest stage

Rule

PRORULE → RULE

51d

Effective on

Wednesday, August 26, 2026

Stage timeline

  1. Proposed·Jul 6, 2026·91 FR 40909

    Schedules of Controlled Substances: Temporary Placement of Mitragynine Pseudoindoxyl, MGM-15, and MGM-16 in Schedule I

    #2026-13581

  2. Final·Aug 26, 2026·91 FR 54948

    Schedules of Controlled Substances: Temporary Placement of Mitragynine Pseudoindoxyl, MGM-15, and MGM-16 in Schedule I

    effective Aug 26, 2026#2026-17429