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The Small Business
Rule Change Brief

Vol. 1 · No. 32

Friday, May 22, 2026

32 issues in archive

Rule lifecycle · RIN:2070-AB27

Significant New Use Rules on Certain Chemical Substances (25-1.5e)

Environmental Protection Agency — observed across 2 documents over 28 days.

In plain English

The EPA requires companies to notify the agency and wait for approval before making or importing certain chemicals in new ways that the EPA hasn't evaluated yet. Your business must submit a notice at least 90 days before starting any new use of these listed chemicals, or you risk fines and product seizure.

First seen

Apr 24, 2026

Last seen

May 22, 2026

Latest stage

Rule

PRORULE → RULE

28d

Effective on

Tuesday, July 21, 2026

Stage timeline

  1. Proposed·Apr 24, 2026·91 FR 22075

    Significant New Use Rules on Certain Chemical Substances (26-2)

    comments close May 26, 2026#2026-08012

  2. Final·May 22, 2026·91 FR 30226

    Significant New Use Rules on Certain Chemical Substances (25-1.5e)

    effective Jul 21, 2026#2026-10264