Rule lifecycle · RIN:2070-AB27

Significant New Use Rules on Certain Chemical Substances (26-1)

Environmental Protection Agency — observed across 4 documents over 47 days. Use the source documents below before deciding whether this affects your business.

In plain English

The EPA is proposing a rule that requires companies to get approval before using certain existing chemicals in new or different ways. If your business uses chemicals in manufacturing or processing, figure out now whether this rule applies to you and prepare to notify EPA before introducing any new chemical uses.

First seen

Apr 24, 2026

Last seen

Jun 10, 2026

Latest stage

Proposed Rule

PRORULE → RULE

28d

Comments close

Friday, July 10, 2026

Stage timeline

  1. Proposed·Apr 24, 2026·91 FR 22075

    Significant New Use Rules on Certain Chemical Substances (26-2)

    comments close May 26, 2026#2026-08012

  2. Final·May 22, 2026·91 FR 30226

    Significant New Use Rules on Certain Chemical Substances (25-1.5e)

    effective Jul 21, 2026#2026-10264

  3. Proposed·Jun 5, 2026·91 FR 34480

    Significant New Use Rules on Certain Chemical Substances (25-3.5e)

    comments close Jul 6, 2026#2026-11319

  4. Proposed·Jun 10, 2026·91 FR 35156

    Significant New Use Rules on Certain Chemical Substances (26-1)

    comments close Jul 10, 2026#2026-11593